Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the NHE-inhibitory efficacy of compounds

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专利权人:

发明人:

申请号：

EP04002943.1

公开号：

EP1420027A3

申请日:

1996.06.07

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and essays for evaluating a compounds therapeutic activity are also disclosed.

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