The present invention relates to substituted benzoxazoles of formula (1) wherein R1 represents a group of the formula, methods for their preparation and diseases, especially cardiovascular disorders, preferably thrombotic disorders or thromboembolic disorders. Relates to their use for the preparation of medicaments for the treatment and / or prevention of. [Chemical formula 1] [Chemical formula 2] [Selected figure] None本発明は、式(1)[式中、R1は式の基を表す]の置換ベンゾキサゾール、それらの調製方法、および、疾患、とりわけ心血管障害、好ましくは血栓性障害または血栓塞栓性障害の処置および/または予防のための薬剤を調製するためのそれらの使用に関する。【化1】【化2】【選択図】なし