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PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
专利权人:
LTD.;HANMI SCIENCE CO.
发明人:
LIM, SE YOUNG,PARK, SUNG HEE,SHIN, RYOUNG AE,CHOI, IN YOUNG,KWON, SE CHANG
申请号:
SG11201404733U
公开号:
SG11201404733UA
申请日:
2013.03.08
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention relates to a pharmaceutical composition for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), including a conjugate prepared by covalently linking an insulinotropic peptide, a non-peptidyl polymer and an immunoglobulin Fc region. The composition of the present invention maintains the in-vivo activity of the peptide at a relatively high level, and remarkably increases the blood half-life, thereby preventing triglyceride accumulation which is a typical feature of non-alcoholic fatty liver disease. Ultimately, it can be desirably employed for the prevention and treatment of non-alcoholic fatty liver disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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