The human simple herpes virus where different kind DNA is installed (HSV) the deoxyribonucleic acid (DNA) being the rearrangement deoxyribonucleic acid which is included, the rearrangement deoxyribonucleic acid which the polypeptide to which aforementioned different kind DNA includes RING finger domain the code is done The rearrangement virus which includes that, the virus vaccine and manner for immunization are offered.< Choice figure >It is not異種DNAが組み込まれたヒト単純ヘルペスウイルス(HSV)デオキシリボ核酸(DNA)を含む組換えデオキシリボ核酸であって、前記異種DNAがRINGフィンガードメインを含むポリペプチドをコードする組換えデオキシリボ核酸;それを含む組換えウイルス、免疫化のためのウイルスワクチンおよび方法が提供される。【選択図】なし