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Inhibitors of crystallization in a solid dispersion
专利权人:
James J. Fort
发明人:
James J. Fort,Steven L. Krill,Devalina Law,Yihong Qiu,Eric A. Schmitt
申请号:
US11691819
公开号:
US09107830B2
申请日:
2007.03.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A pharmaceutical composition is disclosed which comprises a solid dispersion of a pharmaceutical compound in a water soluble carrier, such as polyethylene glycol (PEG), and a crystallization inhibitor, such as polyvinylpyrrolidone or hydroxypropylmethylcellulose. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treatment employing said solid dispersion.
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