6-methoxy-8- [4- (1- (5-fluoro) -quinolin-8-yl-piperidin-4-yl) -piperazin-1-yl] -quinoline crystalline forms

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专利权人:

WYETH

发明人:

JAMES J. BICKSLER,JESSICA K. LIANG

申请号：

BRPI0713101

公开号：

BRPI0713101A2

申请日:

2007.06.08

申请国别(地区):

BR

年份:

2012

代理人:

摘要：

6-METOXY-8- [4- (1- (5-FLUORO) -QUINOLIN-8-IL-PIPERIDIN-4-IL) -PI PERAZIN-1-IL] -QUINOLINE CRYSTALLINE FORMS. The present invention relates to crystalline forms of the 5-HT 1a 6-methoxy-8- [4- (1- (5-fluoro) -quinolin-8-yl-piperidin-4-yl) -piperazinecarboxylic acid binding agent. 1-yl] -quinoline, as well as pharmaceutical compositions thereof, and methods of use thereof.FORMAS CRISTALINAS DE 6-METOXI-8-[4-(1-(5-FLUORO)-QUINOLIN-8-IL-PIPERIDIN-4-IL)-PI PERAZIN-1-IL]-QUINOLINA. A presente invenção refere-se a formas cristalinas do agente de ligação de 5-HT1a 6-metoxi-8-[4-(1-(5-fluoro)-quinolin-8-il-piperidin-4-il)-piperazin-1-il]-qui nolina, bem como composições farmacêuticas das mesmas, e métodos de uso das mesmas.

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