DAVID LEWIS,BRIAN MEAKIN,GAETANO BRAMBILLA,DAVID GANDERTON,ALESSANDRA FERRARIS
申请号:
PT10166800
公开号:
PT2223682E
申请日:
2001.05.18
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
An aerosol solution composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility component to increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler. The composition is stabilized by using a small amount of mineral acid and a suitable can having part or all of its internal metallic surfaces made of stainless steel, anodized aluminium or lined with an inert organic coating.