Multi-filter endolumenal methods and systems for filtering fluids within the body. In some embodiments a multi-filter blood filtering system captures and removes particulates dislodge or generated during a surgical procedure and circulating in a patients vasculature. In some embodiments a dual filter system protects the cerebral vasculature during a cardiac valve repair or replacement procedure. An intravascular blood filter system, comprising: an expandable proximal filter (16), a proximal sheath an expandable distal filter (22) carried by a guiding member (24) and adapted to be collapsed within a distal articulatable sheath (48, 122, 132).
