Provided are a diagnosis assisting device that facilitates a user to grasp adifferenceof an affected area to perform a highly precise diagnosis assistance, an imageprocessingmethod in the diagnosis assisting device, and a program. An image processingmethod in adiagnosis assisting device that diagnoses lesions from a picked-up imageincludes (A)performing an image processing on the picked-up image. In (A), a peripheralarea otherthan a diagnosis area that has a high probability as diseases in the picked-upimage is set tobe a measuring area when an image correction is performed.