表面プラズモン励起増強蛍光分光法を用いた前立腺特異抗原の定量方法
- 专利权人:
- 发明人:
- 申请号：
- JP20110217566
- 公开号：
- JP5726038(B2)
- 申请日:
- 2011.09.30
- 申请国别(地区):
- 日本
- 年份:
- 2015
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a method for quantifying a content, in blood, of a prostate specific antigen (PSA) having a prostate cancer-specific sugar chain, with sensitivity and promptness allowable in diagnostic applications without using a column or the like requiring a process which is complicated though having quantitative properties.
SOLUTION: In the method for quantifying a PSA having aβ-N- acetylgalactosamine residue and/or a fucoseα(1,2) galactose residue at a terminal of a sugar chain by using a surface plasmon-field enhanced fluorescence spectroscopy (SPFS), a lectin of which the affinity with a PSA having aβ-N- acetylgalactosamine residue and/or a fucoseα(1,2) galactose residue at a terminal of a sugar chain is higher than that with a PSA not having these residues at a terminal of a sugar chain is used as capture molecules.
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- 来源网站：
- 中国工程科技知识中心
