PURIFICATION PROCESS FOR PREPARING HIGHLY PURE ARFORMOTEROL TARTRATE SUBSTANTIALLY FREE OF DESFORMYL IMPURITY

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专利权人:

Anant Kishanrao Jagtap

发明人:

Anant Kishanrao Jagtap,Nandkumar Gaikwad,Nikhil Trivedi,Nitin Sharadchandra Pradhan

申请号：

US13215614

公开号：

US20120053246A1

申请日:

2011.08.23

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Provided herein is a highly pure arformoterol tartrate or an amorphous form thereof substantially free of desformyl impurity, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]aniline, process for the preparation thereof, and pharmaceutical compositions comprising the highly pure arformoterol tartrate substantially free of the desformyl impurity.

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