IFOM FONDAZIONE ISTITUTO FIRC DI ONCOGIA MOLECOLARE
发明人:
Valter LONGO,Franca RAUCCI
申请号:
US15761287
公开号:
US20200010562A1
申请日:
2016.09.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to the combination of at least one agent and a reduced calorie intake for use in the treatment of a blood cancer. In particular the agent is a CD20 inhibitor Bruton's tyrosine kinase inhibitor, a phosphoinositide 3-kinase inhibitor, a class I and/class II histone deacetylase inhibitor, a non-taxane replication inhibitor or a proteasome inhibitor. The combination is advantageous in that it sensitize cancer cells to said agent while it protects normal cells from toxicity induced by said agent.