AMIDES DE PYRIDONE DEUTÉRÉS ET LEURS PROMÉDICAMENTS UTILISÉS EN TANT QUE MODULATEURS DE CANAUX SODIQUES

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

申请号：

EP18730543.8

公开号：

EP3625214A1

申请日:

2018.05.16

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. The compounds have the formula (I) wherein R is H or CH2OPO(OH)2. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

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