PROBLEM TO BE SOLVED: To provide a novel pharmaceutical composition comprising a diffusion enhancing compound in an amount sufficient for increasing diffusion of oxygen in plasma and their use in treating a variety of disorders.SOLUTION: The invention provides a pharmaceutical composition comprising a diffusion enhancing compound which increases oxygen diffusion by a kosmotrope such as trehalose and proline in plasma, and a method for treating disorders, for example, respiratory disease such as asthma, cardiovascular disease such as myocardial infarction, Alzheimer's disease, cancer and diabetes by administering the pharmaceutical composition via nasal, parenteral, transdermal, intramuscular injection or oral delivery, thereby increasing diffusion of oxygen in the plasma.SELECTED DRAWING: None【課題】血漿中の酸素の拡散を増加するのに充分な量で拡散促進化合物を含有する新規な医薬組成物、及びそれを用いた、様々な疾患の治療法の提供。【解決手段】トレハロース及びプロリン等コスモトロープの、血漿中の酸素の拡散を増加する拡散促進化合物を含む医薬組成物、及びこれを経鼻、非経口、経皮、筋肉内の注入又は経口送達で投与し、血漿中の酸素の拡散を増加させることにより、喘息等の呼吸器系疾患、心筋梗塞等の循環器系疾患、アルツハイマー病、癌及び糖尿病等の疾患を治療する方法。【選択図】なし
