The present invention provides a novel anhydrous composition of small-molecule polysaccharides, consisting of at least a small-molecule polysaccharide and an anhydrous agent. The anhydrous formulation of the anhydrous composition of small-molecule polysaccharides keeps the molecular size of 12-22 nm of the small-molecule polysaccharide and allows direct penetration of the small-molecule polysaccharide across the horny layer of skin. The present invention also provides a use of small-molecule polysaccharides for the manufacture of an anhydrous composition of small-molecule polysaccharides for effectively maintaining skin moisture.本發明提供一種新穎之小分子多醣無水組成物，係由至少一小分子多醣及一無水基劑組成。該小分子多醣無水組成物的無水配方使該小分子多醣維持分子粒徑約12-22nm且能直接穿透皮膚角質層。本發明亦提供一種小分子多醣用於製備有效維持皮膚含水量之小分子多醣無水組成物的用途。
