Novel process for the preparation of amino acid derivatives

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专利权人:

ウーツェーベー ファルマ ゲーエムベーハー

发明人:

ボウヴィー、ディディエ,マルシャエール、アラン,ピニラ、ヴェロニク,ハマン、ヨルグ,カンツラー、ラルフ,トーマス、アントワーヌ

申请号：

JP2015023801

公开号：

JP6272250B2

申请日:

2015.02.10

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present patent application relates to an alternative process for the preparation of amino derivatives. In particular, the present application relates to an improved process for the manufacture of Lacosamide (LCM), (R)-2-acetamido-N-benzyl-3-methoxypropion-amide, which is useful as an anticonvulsive drug. In a particular aspect, the present invention relates to a process of manufacture of optically enriched (R)-2-acetamido-N-benzyl-3-methoxypropion-amide (I) comprising resolution of 2-acetamido-N-benzyl-3-methoxypropion-amide (II).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/