The Medical College of Wisconsin, Inc.;Costim Pharmaceuticals Inc.
发明人:
申请号:
EP14848888.5
公开号:
EP3049442A4
申请日:
2014.09.25
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to methods of treating hematologic cancers using a combination of inhibitors of PD-1 or PD-L1 and TIM-3, LAG-3 or CTLA-4. In one embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of TIM-3. In another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of LAG-3. In yet another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of CTLA-4.