A gantry free nuclear imaging system (10) images a region of interest (ROI) (16). The system (10) includes one or more radiation detectors (20) generating radiation data indicating the location of gamma photon strikes. The system includes a reconfigurable frame (22) positioning the radiation detectors (20) at fixed viewing angles of the ROI (16) and at least one processor (44, 48). The processor (44, 48) receives the radiation data from the radiation detectors (20) and reconstructs an image of the ROI (16) from the received radiation data.
