KARI ALITALO,Tuomas Tammela,Salla Keskitalo,Katri Pajusola,Markku M. Jeltsch,Seppo Yla-Herttuala,Terhi Karpanen,Ulf Eriksson,Marko J. T. Uutela
申请号:
US13213889
公开号:
US20120071406A1
申请日:
2011.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.