Array Biopharma, Inc.;VentiRx Pharmaceuticals, Inc.
发明人:
HOWBERT, James Jeffry,HERSHBERG, Robert,BURGESS, Laurence E.,YANG, Hong Woon
申请号:
HUE12734770
公开号:
HUE032036T2
申请日:
2012.01.12
申请国别(地区):
HU
年份:
2017
代理人:
摘要:
Provided are benzazepine derivatives useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The benzazepine derivatives have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.