HO WEN-BIN,ZHAO HONGDA,DENG SHAOJIANG,NG DANNY,WRIGHT LEE R.,WU MIN,ZHOU XIAOTI,AREND MICHAEL P.,FLIPPIN LEE A.
申请号:
NZ70076013
公开号:
NZ700760A
申请日:
2013.03.08
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.