A system is disclosed for treating a biologically active surface or material and inerting a protected space. Water is delivered to an anode of an electrochemical cell with the anode and a cathode separated by a proton transfer medium separator. A voltage difference is applied between the anode and the cathode to electrolyze water at the anode to form a mixture of protons and ozone. The protons are transferred across the separator to the cathode, and air is delivered to the cathode where oxygen is reduced to generate oxygen-depleted air, which is directed to the protected space. The ozone is transferred to an ozone storage or distribution system, and ozone is transferred from the ozone storage or distribution system to the biologically active surface or material.
