Methods of inhibiting tumor growth by antagonizing IL-6 receptor

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专利权人:

发明人:

Li Zhang

申请号：

US14329565

公开号：

US09409990B2

申请日:

2014.07.11

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-6 antagonist may be, e.g., an antibody that specifically binds IL-6R. The IL-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.

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