A magnetically-responsive thermally-sensitive fluorescent micelle particle and a preparation method therefor. In the method, N-isopropylacrylamide, N,N-dimethylacrylamide, polylactic acid, etc. are used as raw materials to synthesize a thermosensitive P(NIPAM-co-DMAM)-b-PLA triblock polymer； a dextran-magnetic lamellar composite hydroxide-fluorouracil magnetic sustained-release drug delivery system is assembled at the core of the thermosensitive micelle by simultaneous hydration and dialysis, so as to prepare a magnetically-responsive thermally-sensitive fluorescent micelle having magnetic response and temperature-sensitivity； and water-soluble near-infrared CdHgTe quantum dots (QD) are grafted onto the surface of the magnetically-responsive thermally-sensitive micelle layer using an electrostatic binding technique, so as to finally prepare DMF@TRM@QD fluorescent micellar particles having near-infrared fluorescence emission, magnetic targeting, and thermosensitive controlled-release properties. The product of the present invention features an appropriate LCST, a simple process, low costs, a high drug load, good water solubility, and high sol stability. The micellar particle has ideal thermosensitive properties, magnetic targeting properties, and fluorescent tracer functions, and has special application prospects in the fields of targeted tumor therapy and magnetically induced thermotherapy.La présente invention concerne une particule micelle fluorescente, thermiquement et magnétiquement sensible et son procédé de préparation. Dans le procédé, du N-isopropylacrylamide, du N,N-diméthylacrylamide, du poly(acide lactique), etc. sont utilisés comme matières premières pour synthétiser un polymère à trois blocs thermosensible P(NIPAM-co-DMAM)-b-PLA ； un système d'administration de médicament à libération prolongée magnétique d'hydroxyde-fluorouracile composite, lamellaire, magnétique-dextrane assemblé au cœur de la micelle thermosensible par hydratation et dialyse simultan
