University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Michael B. Chancellor,Johnny Huard,Christopher C. Capelli,Steve Chung,Michael S. Sacks
申请号：
US14972402
公开号：
US20160101217A1
申请日:
2015.12.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
