CHEN ROGER SHEN-CHU,KHALIL EHAB M.,ZHANG WEIHONG,RUCHELMAN ALEXANDER,MAN HON-WAH,MULLER GEORGE W.
申请号:
NZ70005411
公开号:
NZ700054A
申请日:
2011.02.10
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed herein is a compound of formula (II) or (III), wherein the variables are defined in the specification, and the use thereof in the treatment of cancer, a disorder associated with angiogenesis, pain, macular degeneration or a related syndrome, a skin disease, a pulmonary disorder, an asbestos-related disorder, a parasitic disease, an immunodeficiency disorder, a CNS disorder, CNS injury, atherosclerosis or a related disorder, dysfunctional sleep or a related disorder, an infectious disease, hemoglobinopathy or a related disorder or a TNF&alpha related disorder. In one embodiment the compound is 3-(4-(4-(2-morpholinoethoxy)-benzyloxy)-1-oxoisoindolin-2-yl)-piperidine-2,6-dione.