Robert K. Shepherd,John Furness,James Fallon,Sophie Payne,Owen Burns
申请号:
US16335907
公开号:
US20190261912A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Detecting of a disorder associated with impaired barrier function in the gastrointestinal tract of a subject is described, including through determining bioimpedance across a subject's gastrointestinal tract wall and detecting impaired barrier function based on bioimpedance. An electrical signal is measured between first and second electrodes, at least the first electrode being located in a gastrointestinal tract of the body and one or more characteristics are determined based on the measured electrical signal. The one or more characteristics can comprise hallmarks of impaired barrier function such as leakiness and/or permeability of the gastrointestinal tract and can provide an indication of inflammatory bowel disease and/or gut inflammation.