PAYNE, GILLIAN,HERBST, ROBERT W.,BRIDGEWATER, JUMA
申请号：
CA2958882
公开号：
CA2958882A1
申请日:
2015.09.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention provides improved methods for formulating therapeutic compositions comprising an antibody drug conjugate ("ADC") that reduce potency variability between batches of ADC and provide for administration of such therapeutic compositions within a narrow intended range. The current invention provides a novel method for formulating a therapeutic composition comprising an antibody drug conjugate ("ADC") based on drug concentration, thereby narrowing variability in potency between batches of ADC, minimizing toxicity and increasing the efficacy of drug formulated according to this method.
