THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH;THE SCRIPPS RESEARCH INSTITUTE
发明人:
SHEN, WEIJUN,SCHULTZ, PETER G.,MUPPIDI, AVINASH,CRAMERI, ANDREAS,AHMAD, INSHA,YANG, PENGYU
申请号:
CA2924109
公开号:
CA2924109A1
申请日:
2014.09.12
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof.