한양대학교 산학협력단;INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
发明人:
KIM, Seonjeong,김선정,KO, Sachan,고세찬
申请号：
KRKR2017/000931
公开号：
WO2017/131456A1
申请日:
2017.01.26
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a glucose-responsive artificial muscle and, specifically, to: a glucose-responsive artificial muscle based on a carbon nanotube and a hydrogel causing a reversible change in volume according to a change in glucose concentration； a manufacturing method therefor； a rotary artificial muscle using the same； and a method for detecting glucose. According to the present invention, the glucose-responsive artificial muscle provides reversible twisting by using the expansion and contraction, of a hydrogel, occurring because of a change in the charge of inner anions, since boronic acid introduced in the hydrogel is bonded with glucose, and thus a change in glucose concentration can be detected with high sensitivity within a short time. Therefore, the present invention can be usefully applied to: various medical instruments including a drug delivery system, BioMems, bio-nano- and micro-machine, a smart scaffold for tissue engineering, a drug injection channel opening/closing device and a drug injection concentration control device, which are to be regulated according to blood sugar, a neurosimulator and the like； and nanomedicines, the drug delivery field, the rehabilitation medicine field and the bioengineering field.La présente invention concerne un muscle artificiel sensible au glucose et, spécifiquement : un muscle artificiel sensible au glucose à base de nanotube de carbone et un hydrogel causant un changement de volume en fonction d'un changement de concentration de glucose ； un procédé de fabrication de celui-ci ； un muscle artificiel rotatif utilisant celui-ci ； et un procédé de détection de glucose. Selon la présente invention, le muscle artificiel sensible au glucose permet une torsion réversible au moyen de la dilatation et de la contraction, d'un hydrogel, se produisant en raison d'un changement de la charge d'anions internes, étant donné que l'acide borique introduit dans l'hydrogel est lié au glucose et, par conséquent, un changeme
