PYE, PHILIP,BEN HAIM, CYRIL,CONZA, MATTEO,HOUPIS, IOANNIS NICOLAOS
申请号：
PH12015502000
公开号：
PH12015502000A1
申请日:
2015.09.08
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
Disclosed is a process for the preparation of the following compounds: (I), (II) where R1, R1a and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise downstream products, especially compounds that are useful as medicaments, for instance Brutons tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other intermediates and compounds per se.
