System to control a biogas collection plant having a manifold and a plurality of collection units connecting respective capturing wells to the manifold and having respective biogas flow rate regulation valves; the system having a control board with a pressure sensor, a methane sensor, an oxygen sensor, a biogas pressure monitoring network connecting the pressure sensor to the collection units by means of respective control valves, and a chemical biogas monitoring network connecting the methane sensor and the oxygen sensor to the collection units by means of as many control valves; the control board selectively controlling the control valves to measure pressure, methane concentration and oxygen concentration of the biogas in the collection units and controlling the regulation valves as a function of the pressure and methane and oxygen concentration values measured.