Bard Indrevoll,Duncan Hiscock,Bente Elizabeth Arbo,Rajiv Bhalla,Matthias Eberhard Glaser,Graeme Walter McRobbie
申请号：
US13876187
公开号：
US20130189186A1
申请日:
2011.09.27
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to radiopharmaceutical imaging in vivo of apoptosis. The invention provides imaging agents which target apoptotic cells via selective binding to the aminophospholipid phosphatidylethanolamine (PE), which is exposed on the surface of apoptotic cells. The radiopharmaceuticals comprise radiometal complexes of chelator conjugates of PE-binding peptides. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.
