MICHAEL L. CURTIN,MICHAEL R. MICHAELIDES,ROBIN R. FREY
申请号：
BRPI0921392
公开号：
BRPI0921392A2
申请日:
2009.12.04
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Compounds that inhibit protein kinases such as Aurora-kinases and the VEGFR and PDGFR families of kinases, with an improved safety profile due to low CYP3A4 inhibition, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
