A capsule camera device is disclosed, where the capsule camera device comprises multiple light sources with different spectral characteristics for illuminating lumen walls selectively based on a determined capsule location in the gastrointestinal tract. The capsule camera device includes two or more light sources, an image sensor, a battery, a control module and a housing to enclose the above components in a sealed environment. The control module is used to select one or more selected light sources from said at least two light sources depending on a determined capsule location in the GI tract. Only the selected light source or light sources will be used for illumination in the determined capsule location. The light sources may comprise a white light source and a blue light source with a high spectral concentration at about 415 nm or another light source of different spectral characteristics.
