In order to effectively control ion channels of cells a signal (100) is suggested which comprises a first pulse sequence bundle (12a) and a second pulse sequence bundle (12b), each comprising at least two pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein each pulse sequence (11a, 11b, 11c, 11d, 11e, 11f) comprises at least one electromagnetic pulse (10a, 10b, 10c, 10d 10e, 10f). The signal (100) comprises a pulse sequence distance (13a, 13b, 13c) between adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein the signal (100) comprises a first pair (14a) of adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f) and a second pair of adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), each comprising two pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein the signal (100) comprises the same pulse sequence distance between the adjacent pulse sequences (11a, 11b) of the first pair (14a) of pulse sequences (11a, 11b, 11c, 11d, 11e, 11f) and between the adjacent pulse sequences (11d, 11e) of the second pair of pulse sequences (11a, 11b, 11c, 11d, 11e, 11).Afin de contrôler efficacement des canaux ioniques de cellules, un signal (100) est suggéré qui comprend un premier faisceau de séquences dimpulsions (12a) et un second faisceau de séquences dimpulsions (12b), comprenant chacune au moins deux séquences dimpulsions (11a, 11b, 11c, 11d, 11e, 11f), chaque séquence dimpulsions (11a, 11b, 11c, 11d, 11e, 11f) comprenant au moins une impulsion électromagnétique (10a, 10b, 10c, 10d 10e, 10f). Le signal (100) comprend une distance de séquence dimpulsions (13a, 13b, 13c) entre des séquences dimpulsions adjacentes (11a, 11b, 11c, 11d, 11e, 11f), le signal (100) comprenant une première paire (14a) de séquences dimpulsions adjacentes (11a, 11b, 11c, 11d, 11e, 11f) et dune seconde paire de séquences dimpulsions adjacentes (11a, 11b, 11c, 11d, 11e, 11f), comprenant chacune deux séquences dimpulsions (11a, 11b, 11c, 11d, 11e, 11f), le signal (100) comprenant la