What is disclosed is a system and method for assessing peripheral vascular disease from a thermal image captured using a thermal imaging system. In one embodiment the present method involves the following. First, a thermal image is received of a region of exposed skin of a peripheral body part of a subject being monitored for PVD. The thermal image was acquired by a thermal imaging system. Pixels in the thermal image each have a corresponding temperature value. The thermal image is analyzed to stratify the peripheral body part into a plurality of skin surface regions. A skin surface temperature for each respective skin surface region is identified based on pixels in the thermal image associated with those regions. The temperatures are then extracted such that a progression of temperatures can be ascertained. A method for forecasting the progression for future times is also disclosed.