Described in this recornbinante virus like particles (VLPs) Gag Protein of bovine immunodeficiency virus (\"BGAG\")That includes one or more different types of target Proteins of pathogens.Also described are compositions that include the new BGAG VLPs and methods to make and use the new VLP of BGAGSe describen en la presente particulas semejantes al virus recornbinante ("VLP") de la proteina gag del virus de inmunodeficiencia Bovina ("Bgag"), que comprende uno o mas tipos diferentes de proteinas de patogenos objetivo. Tambien se describen, composiciones que comprenden las nuevas VLPs de Bgag y los metodos para hacer y utilizar la nueva VLP de Bgag