Yonggil Kim,Nahmryune Cho,Yunhee Kim,Joon Heo,Seonmin Dong,Mi Kyung Ji,Man-Young Cha,Kiho Lee
申请号:
US13015717
公开号:
US08772299B2
申请日:
2011.01.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to novel piperazine derivatives or pharmaceutically acceptable salts thereof, a process for preparing the same, and in particular, a high binding for Serotonin 1A(5-hydroxytryptamine 5-HT1A) receptor, a pharmaceutical composition for treatment and/or prevention of depression and anxiety including an effective amount of the piperazine compound, and a method of treating depression, anxiety and other conditions related to 5-HT1A receptor in a mammal.