cationic rubonucleic acid (sirna) acid, pharmaceutical compositions, application of cationic rubonucleic acid (sirna) acid and automated synthesis process of a cationic rubonucleic acid (sirna) filament.
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.