USE OF REDD1 INHIBITORS TO DISSOCIATE THERAPEUTIC AND ADVERSE ATROPHOGENIC EFFECTS OF GLUCOCORTICOID RECEPTOR AGONISTS

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专利权人:

发明人:

Irina Budunova,Gleb Baida,Joel Dudley

申请号：

US15046075

公开号：

US20160235763A1

申请日:

2016.02.17

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Disclosed are methods and pharmaceutical compositions for treating diseases, disorders, and conditions associated with glucocorticoid receptor (GR) expression and activity. The disclosed methods typically include administering to a patient in need thereof a glucocorticoid receptor (GR) agonist and administering to the patient in need thereof a REDD1 inhibitor that inhibits expression or activity of REDD1, wherein the REDD1 inhibitor is administered before, concurrently with, or after the GR agonist is administered.

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中国工程科技知识中心

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