Systems and methods are provided for suturing tissue. An elongated deployment shaft carries a needle deployment assembly with needles carrying suture material and a stabilizer that is reconfigurable between an unexpanded insertion profile and an expanded profile. A catcher tube over the shaft having a catcher at a distal end may retain at least a portion of the needles carrying the suture material when the needles are passed through the tissue to be sutured into engagement with the catcher. A sheath over the catcher tube may sandwich tissue to be sutured against the stabilizer when expanded. A first actuator may move the catcher tube distally relative to the shaft to decrease a distance between the proximal end of the stabilizer and the distal end of the stabilizer to expand the stabilizer and may move the sheath distally relative to the shaft to sandwich the tissue. A second actuator may deflect the needles radially outward to move proximally to pass through the tissue to be sutured and engage the catcher and then return a portion of each not retained by the catcher to a distal position for withdrawal of the device.本發明提供用於縫合組織之系統及方法。一延伸部署軸件載送具有縫線之針之一針組傳遞組件,及可在一未經展開插入態樣與一經展開外形之間重新進行組態之一穩定件。在該軸件上之一接針管鞘在一遠端處具有一接針機構,該接針管鞘可在載送該縫線之該等針經過待縫合組織與該接針機構接合時,固持該等針之至少一部分。該接針管鞘上之一管鞘可在該穩定件展開時抵著該穩定件夾置待縫合組織。一第一致動器可使該接針管鞘相對於該軸件遠端地移動,以縮小該穩定件之近端與該穩定件之遠端之間的一距離以展開該穩定件,且可使該管鞘相對於該軸件遠端地移動以夾置該組織。一第二致動器可使該等針徑向地向外偏轉以近端地移動經過該待縫合組織,並接合該接針機構且接著將未由該接針機構固持之每一針之一部分返回至一遠端位置以便撤回裝置。