Frank WEGMANN,Johannes Petrus Maria LANGEDIJK,Jerôme Hubertina Henricus Victor CUSTERS,Viki BOCKSTAL,Markus KALLA
申请号：
US16620669
公开号：
US20200138938A1
申请日:
2018.06.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Poxvirus vectors encoding a synthetic HIV envelope antigen and other HIV antigens, as well as compositions containing such poxvirus vectors and uses of such poxvirus vectors as vaccines to provide improved immunity against HIV, are provided. Also provided are vaccine combinations containing the disclosed poxvirus vectors, adenovirus vectors encoding one or more HIV antigens, and one or more isolated HIV antigenic polypeptides, and methods of using the vaccine combinations to provide improved immunity against HIV.
