Drug formulations having reduced abuse potential which contain one or more of(1) an agent that has a nasty odor, (2) a bright deterrent/indicator dye and(3) fine insoluble particulate matter. The malodorous agent and dye are in aform which does not affect proper administration of the drug, but the odorousagent creates a nasty odor when the dosage form is crushed or chemicallyextracted and nasally, by inhalation, orally, buccally or sublinguallyadministered and the dye produces a bright color when crushed and contacted.The fine insoluble particulate matter hinders extraction of the drug from thedosage form and, when crushed, can deter intravenous injection because of thepresence of the insoluble particles or hinder injection by blocking anintravenous needle. The bright color of the dye, when extracted, also has apsychologically deterrent effect on intravenous abusers.
