Process for the preparation of (4S) - 4 - (cyano - 2-methoxyphenyl) - 5 - ethoxy - 2.8 - dimethyl - 1,4 - dihydro - 1.6 - naftiridina - 3 - carboxamide and purification for use as pharmaceutical Active principle
It refers to a process for the preparation of (4S) - 4 - (cyano - 2-methoxyphenyl) - 5 - ethoxy - 2.8 - dimethyl - 1,4 - dihydro - 1.6 - naftiridina - 3 - carboxamide of formula (i).This acts as an antagonist of the receptor mineralcorticoide nonsteroidal and can be used as a preparation for the prophylaxis and \/ or treatment of cardiovascular and renal InsuficienciTo Cardiac and diabetic nephropathy.Esta referido a un procedimiento para la preparacion de (4S)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetilo-1,4-dihidro-1,6-naftiridina-3-carboxamida de formula (I). Este actua como antagonista no esteroideo del receptor mineralcorticoide y puede emplearse como preparado para la profilaxis y/o tratamiento de afecciones cardiovasculares y renales como insuficiencia cardiaca y nefropatia diabetica.
