COMPOSITIONS COMPRENANT DES EXTRAITS OU DES MATIÈRES DÉRIVÉS DE LIQUEUR VÉGÉTALE D'HUILE DE PALME DESTINÉES À L'INHIBITION DE LA PERTE DE LA VUE DUE À L'ANGIOGENÈSE ET PROCÉDÉ POUR LEUR PRÉPARATION
MOGHADAM, ALI HAFEZI,SAMBANTHAMURTHI, RAVIGADEVI,TAN, YEW AI,P MANICKAM, KALYANA SUNDRAM,HAYES, KENNETH, C.,SOUSKA, ZANDI
申请号:
EP12786044
公开号:
EP2709643A4
申请日:
2012.05.18
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates generally to a composition comprising palm fruit juice for use in a method of preventing and inhibiting vision loss due to angiogenesis related diseases. The composition of the present invention aids to decrease in CNV size using confocal microscopy, in addition to reduction in macrophage infiltration using immune staining; decrease in VEGF- A-induced angiogenesis using established cornea pocket assay, inhibition of IKB-D phosphorylation in laser treated choroidal tissues and reduction in macrophage recruitment to CNV lesions.