EDILSON MARTINS RODRIGUES NETO,KARLA BRUNA NOGUEIRA TORRES BARROS,MARTA MARIA DE FRANÇA FONTELES,SAID GONÇALVES DA CRUZ FONSECA,SANDNA LARISSA FREITAS DOS SANTOS
申请号：
BR102017021229
公开号：
BR102017021229A2
申请日:
2017.10.03
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
development of gel incorporated with Brazilian red propolis to control facial dermal microorganisms. Acne vulgaris is characterized by lesions that result from the action of hormones on the skin's sebaceous glands, affecting the areas with the highest density of sebaceous follicles. The key etiopathogenic factors for the onset of acne are: sebaceous overproduction, follicular canal keratosis, increased bacterial colonization and dermal inflammation. Among the various species, currently Brazilian red propolis has been scientifically distinguished for its distinct chemical composition and broad therapeutic action in various diseases. The chemical composition of propolis depends on the flora of each region visited by the bees and the period of resin collection. Its anti-inflammatory and antioxidant action is related to the presentation of flavonoids, where these therapeutic functions occur through the synergism of these chemical compounds. Brazilian red propolis has been tested for its antimicrobial activity, with good results in vitro and in vivo, which gives credibility to the clinical therapeutic use, but no gel patents with Brazilian red propolis were found. Therefore, because it is an aesthetic clinical condition and difficult to control, production contributes to professionals in the clinical management of acne, as well as to acne patients in improving the therapeutic approach.desenvolvimento de gel incorporados com própolis vermelha brasileira para controle de microrganismos dérmicos faciais. a acne vulgar é caracterizada por lesões que resultam da ação dos hormônios sobre as glândulas sebáceas da pele, afetando as áreas com maior densidade de folículos sebáceos. os fatores etiopatogênicos fundamentais para o surgimento da acne são: hiperprodução sebácea, ceratose do canal folicular, aumento da colonização bacteriana e inflamação dérmica. entre as diversas espécies, atualmente a própolis vermelha brasileira tem se destacado cientificamente por possuir composição
