ACHE LABORATORIOS FARMACEUTICOS S.A;ACHE INTERNATIONAL (BVI) LTD.
发明人:
Valter FREIRE TORRES RUSSO,Elisa Mannochio De Souza Russo
申请号:
US14862667
公开号:
US20160008360A1
申请日:
2015.09.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Alkyl-piperazine-phenyl 4 (3H)-quinazolinones compounds of general formula (I) below are provided that are pharmacologically active and able to act on the 5-HT1A and 5-HT2A serotonin receptors in a manner that promotes the control, relief or cure of disorders associated with these receptors, and pharmaceutical compositions containing the compounds for the treatment of disorders associated with these receptors. These compounds and their pharmaceutical compositions are useful in the treatment of conditions such as depression, anxiety, phobias, addictions, aggressiveness, impulsiveness, panic, psychotic, eating and sleep disorders, obsessive-compulsive disorder and female sexual dysfunctions, including loss of sexual desire, inhibition of sexual desire and absence of sexual desire, among other disorders associated with these receptors.