Mattias ARNOLD;Gabi KASTENMUELLER;Kwangsik NHO;Andrew J. SAYKIN;Rui CHANG;DUKE UNIVERSITY;HELMHOLTZ ZENTRUM MUNCHEN;INDIANA UNIVERSITY SCHOOL OF MEDICINE;MOUNT SINAI SCHOOL OF MEDICINE
发明人:
Rima F. Kaddurah-Daouk,Matthias Arnold,Gabi Kastenmueller,Kwangsik Nho,Andrew J. Saykin,Rui Chang
申请号：
US16488559
公开号：
US20200241011A1
申请日:
2018.02.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to compositions and methods for use in the analysis of broad metabolic changes associated with neurological disorders. In particular, the present disclosure provides materials and methods relating to the use of metabolomics as a biochemical approach to identify sex-specific metabolic biomarkers of neurological disorders. Embodiments of the present disclosure include the use of sex-specific metabolic biomarkers to aid in the determination of whether a subject suffers from, or is at risk of developing, a neurological disorder, such as Alzheimer's disease (AD).
