RODRIGUEZ, FERNANDO,罗奇古斯 佛那度,羅奇古斯 佛那度,SALAS, MARIA LUISA,沙乐丝 玛莉亚 路易莎,沙樂絲 瑪莉亞 路易莎
申请号：
TW103144178
公开号：
TW201610161A
申请日:
2014.12.17
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention is directed to a preferably live attenuated or subsequently inactivated African swine fever virus (ASFV), comprising a non-functional genomic CD2 gene, wherein such ASFV is not deficient in its replication, as well as to corresponding compositions or immunogenic compositions or vaccines, methods of production and uses for treating and/or preventing African swine fever in mammals, preferably of the family Suidae, for instance pigs, more preferably domestic pigs (Sus scrofa domesticus), wild pigs (Sus scrofa scrofa), warthogs (Potamochoerus porcus), bushpigs (Potamochoerus larvatus), giant forest hogs (Hylochoerus meinertzhageni) as well as feral pigs.本發明係關於較佳活的經減毒或後續滅活之非洲豬瘟病毒(African swine fever virus;ASFV),其包含無功能性基因組CD2基因,其中該ASFV在其複製中無缺失,亦係關於相應組合物或免疫原性組合物或疫苗、產生方法及用於治療及/或預防哺乳動物、較佳豬科(Suidae)、例如豬,更佳地馴養豬(家豬(Sus scrofa domesticus))、野豬(歐洲野豬(Sus scrofa scrofa))、疣豬(非洲野豬(Potamochoerus porcus))、藪豬(假面野豬(Potamochoerus larvatus))、大林豬(巨林豬(Hylochoerus meinertzhageni))以及野生豬之非洲豬瘟的用途。
